AD  - Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA. nck6@cdc.gov
TA  - Emerg Infect Dis
LR  - 20041117
DCOM- 20030513
PST - ppublish
AB  - To evaluate transmission dynamics, we exposed 25 bird species to West Nile virus (WNV) by infectious mosquito bite. We monitored viremia titers, clinical outcome, WNV shedding (cloacal and oral), seroconversion, virus persistence in organs, and susceptibility to oral and contact transmission. Passeriform and charadriiform birds were more reservoir competent (a derivation of viremia data) than other species tested. The five most competent species were passerines: Blue Jay (Cyanocitta cristata), Common Grackle (Quiscalus quiscula), House Finch (Carpodacus mexicanus), American Crow (Corvus brachyrhynchos), and House Sparrow (Passer domesticus). Death occurred in eight species. Cloacal shedding of WNV was observed in 17 of 24 species, and oral shedding in 12 of 14 species. We observed contact transmission among four species and oral in five species. Persistent WNV infections were found in tissues of 16 surviving birds. Our observations shed light on transmission ecology of WNV and will benefit surveillance and control programs.
STAT- MEDLINE
LA  - eng
PG  - 311-22
SB  - IM
DA  - 20030319
IP  - 3
EDAT- 2003/03/20 04:00
AU  - Komar N
AU  - Langevin S
AU  - Hinten S
AU  - Nemeth N
AU  - Edwards E
AU  - Hettler D
AU  - Davis B
AU  - Bowen R
AU  - Bunning M
JID - 9508155
OWN - NLM
MHDA- 2003/05/14 05:00
PMID- 12643825
SO  - Emerg Infect Dis 2003 Mar;9(3):311-22.
DP  - 2003 Mar
IS  - 1080-6040
TI  - Experimental infection of North American birds with the New York 1999 strain of West Nile virus.
FAU - Komar, Nicholas
FAU - Langevin, Stanley
FAU - Hinten, Steven
FAU - Nemeth, Nicole
FAU - Edwards, Eric
FAU - Hettler, Danielle
FAU - Davis, Brent
FAU - Bowen, Richard
FAU - Bunning, Michel
MH  - Animals
MH  - Birds
MH  - Culex
MH  - Female
MH  - Male
MH  - Research Support, Non-U.S. Gov't
MH  - Species Specificity
MH  - Viral Load
MH  - West Nile Fever/physiopathology/*transmission
MH  - West Nile virus/*isolation & purification
PL  - United States
VI  - 9
PT  - Journal Article